Bristol-Myers Squibb Company

Bristol-Myers Squibb Company (BMY) Market Cap

Bristol-Myers Squibb Company has a market capitalization of $122.85B.

Financials based on reported quarter end 2025-12-31

Price: $60.17

β–² 1.21 (2.05%)

Market Cap: 122.85B

NYSE Β· time unavailable

CEO: Christopher S. Boerner

Sector: Healthcare

Industry: Drug Manufacturers - General

IPO Date: 1972-06-01

Website: https://www.bms.com

Bristol-Myers Squibb Company (BMY) - Company Information

Market Cap: 122.85B Β· Sector: Healthcare

Bristol-Myers Squibb Company discovers, develops, licenses, manufactures, and markets biopharmaceutical products worldwide. It offers products for hematology, oncology, cardiovascular, immunology, fibrotic, neuroscience, and covid-19 diseases. The company's products include Revlimid, an oral immunomodulatory drug for the treatment of multiple myeloma; Eliquis, an oral inhibitor for reduction in risk of stroke/systemic embolism in NVAF, and for the treatment of DVT/PE; Opdivo for anti-cancer indications; Pomalyst/Imnovid indicated for patients with multiple myeloma; and Orencia for adult patients with active RA and psoriatic arthritis. It also provides Sprycel for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia; Yervoy for the treatment of patients with unresectable or metastatic melanoma; Abraxane, a protein-bound chemotherapy product; Reblozyl for the treatment of anemia in adult patients with beta thalassemia; and Empliciti for the treatment of multiple myeloma. In addition, the company offers Zeposia to treat relapsing forms of multiple sclerosis; Breyanzi, a CD19-directed genetically modified autologous T cell immunotherapy for the treatment of adult patients with relapsed or refractory large B-cell lymphoma; Inrebic, an oral kinase inhibitor indicated for the treatment of adult patients with myelofibrosis; and Onureg for the treatment of adult patients with AML. It sells products to wholesalers, distributors, pharmacies, retailers, hospitals, clinics, and government agencies. The company was formerly known as Bristol-Myers Company. The company was founded in 1887 and is headquartered in New York, New York.

Analyst Sentiment

63%
Buy

Based on 29 ratings

Analyst 1Y Forecast: $61.24

Average target (based on 6 sources)

Consensus Price Target

Low

$40

Median

$60

High

$75

Average

$62

Potential Upside: 3.0%

Price & Moving Averages

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πŸ“˜ Full Research Report

ℹ️

AI-Generated Research: This report is for informational purposes only.

πŸ“˜ Bristol-Myers Squibb Company (BMY) β€” Investment Overview

🧩 Business Model Overview

Bristol-Myers Squibb Company (BMY) is a leading global biopharmaceutical firm focused on the discovery, development, and commercialization of innovative medicines. Its portfolio spans diverse therapeutic areas including oncology, immunology, cardiovascular disease, and fibrosis, addressing critical unmet medical needs. The company’s operations integrate research, clinical development, and worldwide commercialization, reaching healthcare providers, hospitals, pharmacies, and wholesalers across multiple continents. Customers range from government healthcare systems to private insurance networks, as well as individual patients. Bristol-Myers Squibb’s business is underpinned by internal R&D, selective partnerships, and strategic acquisitions, striving to maintain both a robust pipeline and a broad commercial footprint.

πŸ’° Revenue Model & Ecosystem

Bristol-Myers Squibb derives its revenues from a blend of patented prescription drug sales, long-term supply and licensing agreements, co-commercialization partnerships, and rights out-licensing. The core revenue stream revolves around branded pharmaceutical products, particularly specialty and biologic drugs launched via intricate regulatory processes. In addition, the company supplements its top line by leveraging established brands through lifecycle management, extended indications, and entry into new therapies either independently or via collaborations. Revenue is further diversified by global geographic presence, expanding into both mature and emerging healthcare markets and tailoring commercial strategies by region. The company’s engagement model principally serves institutional buyers, payers, and healthcare providers, establishing an ecosystem characterized by multi-stakeholder touchpoints.

🧠 Competitive Advantages

  • Brand strength: Recognized as a premier innovator in biopharma with a legacy of developing life-changing medicines.
  • Switching costs: High physician and patient switching barriers due to drug efficacy, safety profiles, and established payer relationships.
  • Ecosystem stickiness: Durable interactions with healthcare systems, payers, and providers foster long-term integration into treatment protocols.
  • Scale + supply chain leverage: Commanding investment strength in R&D, expansive manufacturing capabilities, and distribution reach, allowing competitive pricing and global access.

πŸš€ Growth Drivers Ahead

Bristol-Myers Squibb's long-term growth prospects are anchored in sustained pipeline innovation, particularly within oncology, immunology, and cardiovascular therapeutics. Ongoing research initiatives, new molecular entities, and next-generation biologics offer opportunities for portfolio enhancement and address significant areas of medical demand. Strategic expansion through business developmentβ€”such as partnerships, in-licensing, and acquisitionsβ€”enables the company to access novel platforms, cutting-edge modalities, and geographic whitespace. Additionally, the life-cycle extension of existing blockbusters through indication expansion, combination regimens, and biosimilar mitigation strategies remains a focal point. The growing prevalence of chronic and rare diseases worldwide enhances the need for advanced therapeutics, positioning BMY to capitalize on evolving healthcare trends.

⚠ Risk Factors to Monitor

Bristol-Myers Squibb operates in a highly competitive landscape defined by rapid scientific progress, patent cliffs, and aggressive peer innovation. Regulatory uncertainty in drug approvals, evolving reimbursement frameworks, and potential pricing pressures from public policy changes pose ongoing risks. Generic and biosimilar competition, especially following loss of exclusivity on major products, can compress margins. Pipeline setbacks, clinical trial failures, and integration challenges from acquisition activity may disrupt anticipated growth. Moreover, technological shifts and new entrants could incrementally erode traditional strongholds, making vigilance toward disruption and operational agility essential for sustained success.

πŸ“Š Valuation Perspective

Within its peer set, Bristol-Myers Squibb generally trades at a valuation reflecting both the strengths of its established product franchises and the competitive/intellectual property risks common in the sector. The company’s profile may lead to its shares being valued in line with or at a modest discount to highly diversified pharma peers, given a relative reliance on a concentrated set of blockbuster products. However, a robust pipeline, disciplined capital allocation, and execution on innovation initiatives can support a re-rating, especially if new launches or acquisitions are perceived as de-risking future cash flows.

πŸ” Investment Takeaway

Bristol-Myers Squibb offers an investment profile anchored by leading therapeutics, a proven commercialization platform, and a strong pipeline poised for future launches. The bullish case centers on the company’s capacity to deliver new therapies, sustain its blockbuster franchises, and capture share in attractive, growing therapeutic categories. Conversely, key risks include patent expirations, regulatory setbacks, and intensifying competition, which could challenge mid- to long-term earnings durability. Investors should weigh the company’s innovation engine and management execution against the backdrop of inevitable industry volatility and external pressures to reach a balanced conclusion.


⚠ AI-generated research summary β€” not financial advice. Validate using official filings & independent analysis.

Fundamentals Overview

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πŸ“Š AI Financial Analysis

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Earnings Data: Q Ending 2025-12-31

"Bristol-Myers Squibb reported a quarterly revenue of $12.50 billion with net income reaching $1.09 billion, resulting in an EPS of $0.53. The net margin stands at approximately 8.7%. The company achieved a robust free cash flow of $5.99 billion. Year-over-year growth shows steady performance in core pharmaceutical operations. Bristol-Myers Squibb's growth is solid, rooted in its pharmaceutical products, though revenue growth appears modest. Profit margins and net income indicate efficiency in operations. The substantial free cash flow highlights good liquidity, supporting dividend payments of $1.26 billion for the quarter. The company has maintained a strong balance sheet with total assets of $106.73 billion against liabilities of $45.11 billion, resulting in a total equity of $55.78 billion. Despite strong cash reserves ($15.73 billion), the net debt position is negative, indicating net cash holdings. As for shareholder returns, maintaining a steady dividend reflects positively. Analyst sentiment shows a mixed outlook with a high price target of $66 and a low of $37, while consensus averages at $56.67. Valuation appears reasonable given the stable cash flows and moderate growth expectations."

Revenue Growth

Positive

Revenue showed steady growth supported by pharmaceutical products but remains at a modest rate.

Profitability

Good

Operating margins and net income are solid, reflecting efficient operations with a net margin of 8.7%.

Cash Flow Quality

Strong

Free cash flow of $5.99 billion is strong, ensuring liquidity and supporting stable dividend payouts.

Leverage & Balance Sheet

Good

The balance sheet is strong with ample net cash and low leverage, enhancing financial resilience.

Shareholder Returns

Good

Consistent dividend payments highlight a commitment to shareholder returns, though no repurchases observed.

Analyst Sentiment & Valuation

Positive

Analyst sentiment is mixed but shows reasonable valuation with a consensus price target reflecting steady sentiment.

Disclaimer:This analysis is AI-generated for informational purposes only. Accuracy is not guaranteed and this does not constitute financial advice.

BMY delivered a solid Q4 with strong growth from its newer portfolio largely offsetting legacy declines, and issued 2026 guidance that underscores continued top-line resilience, disciplined cost control, and robust cash generation. The pipeline is entering a catalyst-rich period with multiple pivotal readouts and label expansion opportunities, while AI-enabled productivity and a fortified balance sheet support investment. Management remains confident, though LOE-driven pressure, margin mix headwinds, and a flagged 2027 Eliquis step-down temper the otherwise constructive outlook.

Growth

  • Growth portfolio revenue up 15% in Q4 and 17% for FY25; ~60% of Q4 total revenue
  • Opdualag, Breyanzi, and Camzyos each exceeded $1B in FY25 sales; Reblozyl exceeded $2B
  • Q4 product highlights: Breyanzi +47%; Camzyos +57% ($353M); Reblozyl +21%; Opdivo +7% (~$2.7B); Eliquis +6% (~$3.5B); Opdualag double-digit growth; Qvantik $133M; CoBinfy $51M; Sotyktu +3%

Business Development

  • Breyanzi received FDA approval in relapsed/refractory marginal zone lymphoma (now approved across five cancer types)
  • Partnership with BioNTech: reported first global phase 2 pemigatinib data in TNBC; planning to have eight registrational studies underway by YE26, including new NSCLC studies (unresectable stage 3 and 1L high PD-L1)
  • Initiated global phase 3 Break Free SSC for Zolacel (CD19 CAR T) in active systemic sclerosis
  • Nablometastat (PRMT5 inhibitor) oral combination data to be presented at ESMO TAT next month
  • Ongoing investment in external innovation, including the Orbital Therapeutics program; 2025 included a non-deductible IPR&D charge related to the Orbital acquisition

Financials

  • Q4 revenue β‰ˆ$12.5B, flat y/y; growth portfolio $7.4B (+15%)
  • Q4 gross margin 71.9% (-210 bps) on product mix (notably Eliquis up; Revlimid down)
  • FY25 operating expenses (ex IPR&D) $16.6B, down $1.2B y/y; ~$1B of $2B cost-savings target achieved
  • Q4 non-GAAP EPS $1.26; FY25 non-GAAP EPS $6.15; includes IPR&D/licensing net charges of $0.60 (Q4) and $1.40 (FY)
  • Q4 effective tax rate 22.1% vs 19.9% prior year, impacted by non-deductible IPR&D
  • 2026 guidance: revenue $46–$47.5B; gross margin 69–70%; total opex β‰ˆ$16.3B; OI&E expense β‰ˆ$700M (diabetes royalties expired end-2025); tax rate β‰ˆ18%; non-GAAP EPS $6.05–$6.35

Capital & Funding

  • Cash and marketable securities β‰ˆ$11B as of 12/31/2025
  • Completed $10B debt paydown ahead of schedule
  • Operating cash flow β‰ˆ$2B in Q4
  • Capital allocation priorities: business development and sustaining the dividend

Operations & Strategy

  • Executing a multiyear plan to β€˜rewire’ for long-term growth; emphasis on β€˜say-to-do’ culture
  • AI adoption to operate leaner, move faster, and reinvest in growth
  • Cost-savings program on track to deliver remaining ~$1B over 2026–2027
  • Commercial execution: Camzyos launched in >50 countries and prescriber base expanding; CoBinfy access and adoption growing across community and hospital settings; Qvantik early uptake; Opdivo growth via new indications

Market & Outlook

  • 2026: continued strength from growth portfolio; legacy portfolio expected to decline 12–16% due to LOE
  • Eliquis expected to grow 10–15% in 2026 (demand growth, price reduction expanding access and removing inflation penalty); 2H sales to exceed 1H; typical Q1 destocking expected
  • Company expects six top-line registrational readouts in 2026: Nilvexin (AFib; secondary stroke prevention), admilparent (IPF), iberdomide (MM), mozignamide (RR MM), arlocell (RR MM), and RAISE-101 (2L+ GAP NETs)
  • Additional pivotal readouts: Sotyktu in lupus; CoBinfy in Alzheimer’s disease psychosis; Sotyktu PDUFA for psoriatic arthritis; phase 3 readouts in lupus and SjΓΆgren’s
  • Nablometastat oral combo data at ESMO TAT next month; multiple pivotal readouts weighted to 2H26

Risks Or Headwinds

  • Ongoing LOE and generic erosion in legacy portfolio
  • Gross margin pressure from unfavorable mix (higher Eliquis; lower Revlimid/Pomalyst)
  • Execution and regulatory risks tied to numerous pivotal trials and launches
  • Eliquis sales expected to step down by $1.5–$2.0B in 2027 vs 2026
  • Seasonal Q1 inventory destocking and pricing dynamics

Sentiment: MIXED

Note: This summary was synthesized by AI from the BMY Q4 2025 earnings transcript. Financial data is complex; please verify all metrics against official SEC filings before making investment decisions.

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SEC Filings (BMY)

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