Eli Lilly and Company

Eli Lilly and Company (LLY) Market Cap

Eli Lilly and Company has a market capitalization of $875.88B.

Financials based on reported quarter end 2025-12-31

Price: $927.03

23.04 (2.55%)

Market Cap: 875.88B

NYSE · time unavailable

CEO: David A. Ricks

Sector: Healthcare

Industry: Drug Manufacturers - General

IPO Date: 1972-06-01

Website: https://www.lilly.com

Eli Lilly and Company (LLY) - Company Information

Market Cap: 875.88B · Sector: Healthcare

Eli Lilly and Company discovers, develops, and markets human pharmaceuticals worldwide. It offers Basaglar, Humalog, Humalog Mix 75/25, Humalog U-100, Humalog U-200, Humalog Mix 50/50, insulin lispro, insulin lispro protamine, insulin lispro mix 75/25, Humulin, Humulin 70/30, Humulin N, Humulin R, and Humulin U-500 for diabetes; and Jardiance, Trajenta, and Trulicity for type 2 diabetes. The company provides Alimta for non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma; Cyramza for metastatic gastric cancer, gastro-esophageal junction adenocarcinoma, metastatic NSCLC, metastatic colorectal cancer, and hepatocellular carcinoma; Erbitux for colorectal cancers, and various head and neck cancers; Retevmo for metastatic NSCLC, medullary thyroid cancer, and thyroid cancer; Tyvyt for relapsed or refractory classic Hodgkin's lymph and non-squamous NSCLC; and Verzenio for HR+, HER2- metastatic breast cancer, node positive, and early breast cancer. It offers Olumiant for rheumatoid arthritis; and Taltz for plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and non-radiographic axial spondylarthritis. The company offers Cymbalta for depressive disorder, diabetic peripheral neuropathic pain, generalized anxiety disorder, fibromyalgia, and chronic musculoskeletal pain; Emgality for migraine prevention and episodic cluster headache; and Zyprexa for schizophrenia, bipolar I disorder, and bipolar maintenance. Its Bamlanivimab and etesevimab, and Bebtelovimab for COVID-19; Cialis for erectile dysfunction and benign prostatic hyperplasia; and Forteo for osteoporosis. The company has collaborations with Incyte Corporation; Boehringer Ingelheim Pharmaceuticals, Inc.; AbCellera Biologics Inc.; Junshi Biosciences; Regor Therapeutics Group; Lycia Therapeutics, Inc.; Kumquat Biosciences Inc.; Entos Pharmaceuticals Inc.; and Foghorn Therapeutics Inc. Eli Lilly and Company was founded in 1876 and is headquartered in Indianapolis, Indiana.

Analyst Sentiment

78%
Strong Buy

Based on 31 ratings

Analyst 1Y Forecast: $1133.86

Average target (based on 6 sources)

Consensus Price Target

Low

$985

Median

$1280

High

$1350

Average

$1245

Potential Upside: 34.3%

Price & Moving Averages

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📘 Full Research Report

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AI-Generated Research: This report is for informational purposes only.

📘 Eli Lilly and Company (LLY) — Investment Overview

🧩 Business Model Overview

Eli Lilly and Company is a global pharmaceutical leader focused on developing, manufacturing, and commercializing medicines across several therapeutic areas. The company’s core products span treatments for diabetes, oncology, immunology, neuroscience, and other complex conditions. Its customer base includes healthcare providers, hospitals, retail pharmacies, government agencies, and patients worldwide. Operating in both developed and emerging markets, Eli Lilly leverages a network of research facilities, manufacturing plants, and distribution partners to ensure steady access to its innovations. The firm's business model is rooted in ongoing investments in scientific research, intellectual property, and collaborations with academic, clinical, and biotech partners to maintain a robust pipeline of new therapies.

💰 Revenue Model & Ecosystem

Eli Lilly’s revenue generation relies on a multi-stream model primarily driven by proprietary pharmaceuticals. The company benefits from exclusive patent rights on innovative drugs, allowing for premium pricing during the exclusivity window. After patent expiry, legacy products may continue to generate revenue through established brand recognition, although generic competition often reduces margins. The ecosystem is enhanced by ongoing investments in life-cycle management, companion diagnostics, drug-device combinations, and digital health initiatives that complement core medicine offerings. Revenue sources are diversified across various therapeutic fields, and the company serves a mix of enterprise channels—including government tenders, healthcare systems, and institutional buyers—alongside direct engagement with patients and providers through support programs, education, and branded health initiatives.

🧠 Competitive Advantages

  • Brand strength: Lilly is recognized globally for scientific innovation, trustworthiness, and its legacy in chronic disease management.
  • Switching costs: Specialized therapies, physician familiarity, and patient support programs can create high barriers to switching, especially for complex conditions.
  • Ecosystem stickiness: Partnerships with providers, integration of digital tools, and a wide spectrum of therapeutic indications foster ongoing engagement across the care continuum.
  • Scale + supply chain leverage: Global reach, robust manufacturing infrastructure, and long-established distribution networks ensure operational resilience and cost efficiencies that are challenging for smaller rivals to replicate.

🚀 Growth Drivers Ahead

Eli Lilly is well-positioned to capture multi-year growth from both internal and external catalysts. The company’s research pipeline includes next-generation medicines across high-value therapeutic areas such as metabolic disorders, oncology, immunology, and neurological diseases. Recent advances in biologics, gene therapies, and digital medicine provide new avenues for long-term differentiation. Strategic acquisitions, licensing arrangements, and global partnerships continuously replenish the pipeline and enable expansion into new patient segments and geographies. Additionally, the company’s investments in manufacturing technology, supply chain modernization, and data-driven healthcare solutions position it to scale new product launches efficiently. Secular trends, including aging populations and rising prevalence of chronic illness, further underpin long-run demand for Lilly’s core competencies.

⚠ Risk Factors to Monitor

Several structural risks could impact Eli Lilly’s investment thesis. The company faces intense competition from other major pharmaceutical firms and biotechs, both in the discovery of new medicines and in the erosion of exclusivity as patents expire. Regulatory dynamics—including drug pricing scrutiny, reimbursement negotiations, and evolving safety standards—pose ongoing challenges. Margin pressure can arise from increased R&D costs, pricing headwinds, or unfavorable product mix changes. Furthermore, breakthrough therapies or disruptive technologies from competitors, as well as operational risks in large-scale manufacturing and global supply chains, are important variables for investors to monitor closely.

📊 Valuation Perspective

The market often assigns Eli Lilly a premium valuation relative to traditional pharmaceutical peers. This is attributable to the company’s robust innovation track record, growth potential in high impact therapeutic areas, and perceived resilience of its brand and pipeline. The breadth of its late-stage assets and demonstrated ability to commercialize new blockbusters support investor confidence in future cash flows. However, premium valuation multiples may also reflect elevated expectations for execution, continued pipeline productivity, and effective response to market and regulatory challenges.

🔍 Investment Takeaway

Eli Lilly offers investors a blend of established market leadership, exposure to innovative therapeutics, and strong brand equity. The bullish case hinges on the company's capacity to consistently deliver new high-impact drugs, maintain regulatory and operational discipline, and capitalize on global healthcare trends. On the other hand, the bearish case focuses on heightened competition, regulatory risks, and the inherent uncertainty tied to drug development. As with any large-cap pharmaceutical investment, careful monitoring of pipeline progress, intellectual property sustainability, and evolving healthcare policy is essential in balancing long-term risk and reward.


⚠ AI-generated research summary — not financial advice. Validate using official filings & independent analysis.

Fundamentals Overview

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📊 AI Financial Analysis

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Earnings Data: Q Ending 2025-12-31

"For the quarter ending December 31, 2025, Lilly reported revenue of $19.29 billion with a net income of $6.64 billion, reflecting a strong net margin despite a zero EPS figure reported for the quarter. Free cash flow was notably solid at $8.61 billion, demonstrating significant liquidity and cash generation. Year-over-year growth appears robust, underscored by stable revenue performance. Growth is primarily driven by strong sales across its pharmaceutical products. Profitability remains high, as indicated by the notable net income figure, although the EPS detail is absent, which might reflect adjustments or exceptional items not detailed in the report. With a balance sheet characterized by a substantial level of total liabilities compared to equity, the net debt position stands at $32.71 billion, suggesting a moderate level of leverage. The company’s ability to generate substantial free cash flow supports sustainable dividend payments, evident in regular and increasing dividend payout. Valuation sentiment appears positive with a consensus price target of $1,150.93, amidst an anticipated price range of $830 to $1,300, reflecting analysts' confidence in the stock’s potential. Shareholder returns are highlighted by ongoing dividends and share repurchase activities, reinforcing the company's commitment to capital returns to investors."

Revenue Growth

Good

Solid revenue growth driven by strong demand in core products with consistent quarterly progression.

Profitability

Strong

High net income indicates exceptional profitability, although the EPS reporting requires clarification.

Cash Flow Quality

Strong

Very strong free cash flow supports liquidity and robust dividend payments, suggesting operational efficiency.

Leverage & Balance Sheet

Neutral

Balance sheet leverage is moderate with net debt high relative to equity, but manageable with strong cash flows.

Shareholder Returns

Good

Consistent and growing dividend payments alongside share buybacks enhance shareholder value.

Analyst Sentiment & Valuation

Good

Consensus price targets reflect favorable market sentiment, indicating potential upside and stock confidence.

Disclaimer:This analysis is AI-generated for informational purposes only. Accuracy is not guaranteed and this does not constitute financial advice.

Lilly delivered a strong Q4 and FY25 with broad-based volume growth led by Zepbound and Mounjaro, significant pipeline progress, and rapid manufacturing scale-up. Management guided to another year of robust top- and bottom-line growth in 2026 despite notable pricing headwinds from access expansions and international reimbursement. The tone was confident, highlighting market leadership in incretins, expanding Alzheimer’s presence with Kisanlo, and a deep late-stage pipeline, while acknowledging near-term price and margin pressures from access agreements and new capacity ramps.

Growth

  • FY25 revenue $65.2B, +45% YoY; EPS $24.21, +86% YoY
  • Q4 revenue +43% YoY; non-GAAP performance margin 47.2% (+4.2pp)
  • Key products generated >$13B in Q4 revenue, +91% YoY
  • Combined incretin market TRx +33% YoY in the US
  • Zepbound revenue more than doubled vs Q4 2024; ~70% share of new obesity Rxs
  • Mounjaro >55% US new Rxs in T2D incretin market; incretin share leader ex-US
  • Kisanlo US market leader in amyloid therapies (>50% TRx); Q4 revenue $109M
  • Eblis TRx +25% vs Q3 2025; Omvo revenue +55% YoY; Jayperca sales +30% YoY; Verzenio +3% YoY
  • Ex-US volume growth double-digit in Europe/Japan/China; Rest of World volume doubled

Business Development

  • Executed 39 transactions across therapeutic areas in 2025
  • Added clinical-stage assets via Scorpion, FERV, SiteOne, Adverum; announced upcoming Ventix acquisition
  • AI collaboration with NVIDIA to open a co-innovation lab; added new supercomputer for drug discovery

Financials

  • Q4 gross margin 83.2% (flat YoY); favorable mix and lower COGS offset by lower realized prices
  • Q4 R&D +26% YoY; SG&A +29% YoY; effective tax rate 19.7%
  • Q4 EPS $7.54 (incl. $0.52 acquired IPR&D) vs $5.32 (incl. $0.19) in Q4 2024
  • US Q4 revenue +43% with ~7% price decline; strong ex-US volume growth
  • 2026 guidance: revenue $80–$83B (midpoint +25% YoY); EPS $33.50–$35; performance margin 46%–47.5%
  • 2026 price drag expected low-to-mid-teens (Medicare/Medicaid obesity access agreement, DTP Zepbound pricing, lower Medicaid prices; China NRDL impact on Mounjaro)

Capital & Funding

  • Committed >$55B to manufacturing expansion since 2020
  • Returned $1.3B in dividends and $1.5B via share repurchases in 2025
  • Began production at new sites in Wisconsin and North Carolina; new sites planned in US and Europe

Operations & Strategy

  • Exceeded goal to produce 1.8x incretin doses in 2025 vs 2024; ongoing global manufacturing build-out
  • Completed international rollouts of Mounjaro and Kisanlo
  • US direct-to-patient platform reached 1M patients in 2025; Zepbound self-pay vials one-third of new obesity med starts across brands
  • In Q4, Zepbound vials ~1/3 of total Zepbound Rxs and ~50% of new Zepbound Rxs
  • Submitted Orforglipron for obesity in the US and >40 countries; progressed Retatrutide
  • Started 14 new Phase 3 programs (incl. Oloralintide, Brenepatide); 36 active Phase 3 programs
  • Positive Together PSA Phase 3b: ixekizumab + tirzepatide improved psoriatic arthritis outcomes vs ixekizumab alone
  • Pirtobrutinib (Jayperca) received full FDA approval with expanded CLL/SLL indication; additional filings for earlier lines submitted
  • Sofetibart mepetekcan (FRα ADC) advanced to Phase 3; FDA Breakthrough Therapy Designation; planning platinum-sensitive study
  • Planned new Phase 3s: tirsolecimid (PI3Kα), vepubratinib (FGFR3); Imlunestrant combo data submitted; large adjuvant breast cancer trial (EMBER-4) fully enrolled
  • Presenphatide (GIP/GLP-1) moved into Phase 2 asthma; Brenepatide in Phase 3 for alcohol use disorder and Phase 2 for tobacco use and bipolar disorder
  • Donanemab prevention study (Trailblazer ALS3) ongoing; event-driven readout with projected primary completion 2027

Market & Outlook

  • Expect sustained robust growth in incretin markets; obesity penetration still mid-single digits
  • Orforglipron US launch for chronic weight management anticipated in 2026; most international launches in 2027
  • Medicare access to obesity medicines expected effective no later than July 1, 2026
  • 2026 Medicaid obesity coverage to decline in some states (e.g., California); new state additions expected in 2027
  • China NRDL inclusion for Mounjaro in T2D to pressure price but expand access
  • Growth in 2026 expected from Eblis, Jayperca, Inlureo, Kisanlo, Omvo; late lifecycle products (Trulicity, Talsa, Verzenio) expected flat to down
  • Oral GLP-1 launches expected to expand the addressable market

Risks Or Headwinds

  • Lower realized prices in the US (Q4 US price -7% YoY) and expected low-to-mid-teens price drag in 2026
  • Pricing concessions tied to Medicare/Medicaid access agreement and DTP Zepbound pricing
  • China NRDL pricing pressure for Mounjaro
  • Potential gross margin pressure from new facilities coming online
  • Higher R&D and SG&A to support large pipeline and multiple launches
  • Late lifecycle product declines (Trulicity, Talsa, Verzenio) could offset growth

Sentiment: POSITIVE

Note: This summary was synthesized by AI from the LLY Q4 2025 earnings transcript. Financial data is complex; please verify all metrics against official SEC filings before making investment decisions.

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SEC Filings (LLY)

© 2026 Stock Market Info — Eli Lilly and Company (LLY) Financial Profile