Spyre Therapeutics, Inc.
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Spyre Therapeutics, Inc. (SYRE)

Profitability & Net Margin History

Current Net Margin

-69.10%

Spyre Therapeutics, Inc. currently has a net profit margin of -69.10%.

Financial Fundamentals

SYREQuarterly Data • 5Y View

Historical Margin Data

DateRev ($B)NI ($B)Net MarginChange (bps)
2025-12-310.09-0.06-69.10%
2025-09-300.00-0.01
2025-06-300.00-0.04
2025-03-310.00-0.04
2024-12-310.00-0.06
2024-09-300.00-0.07
2024-06-300.00-0.04
2024-03-310.00-0.04
2023-12-310.00-0.06
2023-09-300.00-0.04
2023-06-300.00-0.22-31552.47%2224843
2023-03-310.00-0.02-9304.04%189953
2022-12-310.00-0.02-11203.57%72426
2022-09-300.00-0.02-10479.31%690763
2022-06-300.00-0.02-3571.68%177755
2022-03-310.00-0.02-1794.13%123304
2021-12-310.00-0.02-561.09%89045
2021-09-300.00-0.02-1451.54%140167
2021-06-300.01-0.01-49.87%
2021-03-310.00-0.02
2020-12-310.00-0.02
2020-09-300.00-0.02
2020-06-300.00-0.02
2020-03-310.00-0.02
2019-12-310.00-0.02
2019-09-300.00-0.02
2019-06-300.00-0.02
2019-03-310.00-0.02
2018-12-310.00-0.01
2018-09-300.00-0.01
2018-06-300.00-0.01-395.88%14180
2018-03-310.00-0.01-537.68%10023
2017-12-310.00-0.01-437.45%18698
2017-09-300.00-0.01-624.43%17601
2017-06-300.00-0.01-448.41%18774
2017-03-310.00-0.01-636.15%19646
2016-12-310.00-0.01-439.70%10321
2016-09-300.00-0.01-542.91%14742
2016-06-300.00-0.01-395.48%13385
2016-03-310.00-0.00-529.34%27779
2015-12-310.00-0.00-251.55%6653
2015-09-300.00-0.00-318.08%27644
2015-06-300.00-0.00-41.64%
2015-03-310.00-0.00
2014-12-310.00-0.00
2014-09-300.00-0.00
2014-06-300.00-0.00
2014-03-310.00-0.00

* Basis Point (bps) change measures sequential efficiency shifts. 100 bps = 1.00% Margin change.